Research

IN THIS SECTION 1. Overview 2. Research Focus 3. Projects 4. Publications

 

Publications

1996-1999

1999

Goldfine SM, Walcott B, Brink PR, Magid NM, Borer JS. Myocardial connexin43 expression in  hypertrophy resulting from aortic regurgitation. Cardiovascular Pathology 1999; 8:1-6.

Borer JS. Background therapy in congestive heart failure studies, in Cardiovascular Drug Development (Borer JS, Somberg J, eds) Marcel Dekker: New York,1999, pp. 49-56

Borer JS, Somberg JC. Angiotensin converting enzyme inhibitors for mortality reduction in congestive heart failure: should approval be granted for a class effect?, in Cardiovascular Drug Development(Borer JS, Somberg J, eds)  Marcel Dekker: New York,1999, pp. 63-70.

Borer JS. Calcium channel blockers: safety issues, in Cardiovascular Drug Development (Borer JS, Somberg J, eds)  Marcel Dekker:New York,1999, pp. 107-120.

Borer JS. Future directions of cardiovascular drug development,in Cardiovascular Drug Development (Borer JS, Somberg J, eds) Marcel Dekker: New York,1999, pp. 213-222.

Shaffer B, Borer JS. Edema and foot injuries: pathophysiology and differential diagnosis, Disorders of the Heel, Rearfoot and Ankle(Ranawat CS and Positano RG, eds), New York: Churchill Livingstone, 1999, pp. 116-124.

Packer M, Cohn JN, eds (Contributing authors incl. Borer JS). Consensus recommendations for the management of chronic heart failure. American Journal of Cardiology 1999;83 (Suppl 2A):1A- 38A.

Cerqueira MD (Chairman), Mahmarian JJ, Borer, JS, Botvinick EH, Gibbons RJ, Maddahi J, Miller D, Pieri P, Schwartz RG. Monitoring aggressive therapy for CAD  (in Zaret, ed, Wintergreen Nuclear Cardiology Retreat Panel Reports). J Nucl Cardiology 1999;6:148-155.

Somberg JC, Borer JS. Advances in cardiovascular pharmacology: protocol design and   methodology -–the US regulatory process. American Journal of Therapeutics 1999; 6:175-178.

Borer JS, Herrold EM, Hochreiter CA, Truter SL, Carter JN, Goldfine SM. Pathophysiology of heart failure in regurgitant valvular diseases: relation to ventricular dysfunction and clinical debility, in Molecular Cardiology in Clinical Practice (Sanders MR and Kostis JB, eds), Boston: Kluwer Academic, 1999, pp. 43-56.

Supino PG, Borer, J.S., Herrold EM, Hochreiter C. Prognostication in 3-vessel coronary artery    disease based on left ventricular ejection fraction during exercise: influence of coronary artery bypass grafting. Circulation, 1999;100:924-932.

1998

Okin PM, Roman MJ, Devereux RB, Pickering TG, Borer JS, Kligfield P. Time-voltage QRS area of the 12-lead electrocardiogram: detection of left ventricular hypertrophy. Hypertension 1998;31:937-942.

Goldfine SM, Pena M, Magid NM, Liu S-K, Borer JS. Myocardial collagen in cardiac hypertrophy resulting from chronic aortic regurgitation. American Journal of Therapeutics 1998;5:139-146.

Borer JS. Measurement of ventricular function and volume, in Nuclear Cardiology: State of the   Art and Future Directions, 2nd Edition (Eds.: Zaret B, and Beller G), Mosby: St. Louis,1998, pp. 201-215.

Ross JS, Goldfine SM, Herrold EM, Borer JS. Differential response to vesnarinone by cardiac fibroblasts isolated from normal and aortic regurgitant hearts. American Journal of Therapeutics 1998; 5:369-375.

Borer JS, Hochreiter C, Herrold EM, Supino P, Aschermann M, Wencker D, Devereux RB, Roman MJ, Szulc M, Kligfield P, Isom OW. Prediction of indications for valve replacement     among asymptomatic or minimally symptomatic patients with chronic aortic regurgitation and normal left ventricular performance.  Circulation 1998; 97:525-534.

Liu S-K, Magid NM, Fox PR, Goldfine SM, Borer JS. Fibrosis, myocyte degeneration and heart failure in chronic experimental aortic regurgitation. Cardiology, 1998; 90:101-109.

1997

Freed LA, Stein KM, Borer JS, Hochreiter C, Supino P, Devereux RB, Roman MJ, Kligfield P. Relation of ultra-low frequency heart rate variability to the clinical course of chronic aortic regurgitation. American Journal of Cardiology 1997; 79:1482-1487.

 Schussheim AE, Devereux RB, de Simone G, Borer JS, Herrold EM, Laragh JH. Usefulness of subnormal midwall fractional shortening in predicting left ventricular exercise dysfunction in asymptomatic patients with systemic hypertension. American Journal of Cardiology 1997;79:1070-1074.

Reisin L, Marmor A, Rabinowitz B, Bernink PJLM, Caspi A, Ruzyllo W, Borer JS, and the Alprostadil Investigators. Safety of prostaglandin E1 for the treatment of peripheral arterial  occlusive disease in patients with congestive heart failure. American Journal of Therapeutics,  1997;4:365-374.

Somberg J, Yelamanchi V, Molnar J, Aschermann M, Bernink PJLM, Caspi A, Marmor A,  Rabinowitz B, Reisin L, Ruzyllo W, and the Alprostadil Investigators (incl. Borer JS).           Prostaglandin E1: electrophysiological safety in patients with CHF and peripheral arterial occlusive disease. American Journal of Therapeutics 1997;4:401-404.

Lu P, Zanzonico P, Goldfine SM, Hardoff R, Magid N, Gentile R, Herrold EM, Borer JS. Antimyosin antibody imaging in experimental aortic regurgitation. Journal of Nuclear Cardiology 1997;4:25-32.

King RK, Magid NM, Opio G, Borer JS. Protein turnover in compensated chronic aortic regurgitation. Cardiology 1997;.88:518-525.

1996

Borer JS, Wencker D, Hochreiter C. Management decisions in valvular heart disease: the role of radionuclide-based assessment of ventricular function and performance. Journal of Nuclear Cardiology 1996; 3:72-81.

Borer JS. Reverse redistribution - "Part II": Occurrence after thallium reinjection. Journal of Nuclear Medicine 1996; 37:742-743.

Lu P, Zanzonico P, Lister-James J, Golfine SM, Herrold EM, Lees RS, Lees AM, Dean R, Moyer BR, Borer JS. Biodistribution and autoradiographic localization of I-125-labeled synthetic peptide in aortic atherosclerosis in cholesterol-fed rabbits. American Journal of Therapeutics 1996; 3:673-680.

Lu P, Wencker D, Szulc M, Supino P, Mueller R, Zola B, Casadei GR, Zanzonico P, Herrold EM, Borer JS. Computer-aided quantitation of the effect of nitroglycerin and isosorbide dinitrate on thallium-201 redistribution in patients with myocardial infarction. Computers in Cardiology, 1996; IEEE Publication #0276-6547/96:337-340.

Chen J, Okin P, Roman MJ, Hochreiter C, Devereux RB, Borer JS, Kligfield P. Combined rest  and exercise electrocardiographic repolarization findings in relation to structural and functional abnormalities in asymptomatic aortic regurgitation. American Heart Journal 1996;132:343-347.

Kroll DJ, Freed LA, Stein KM, Borer JS, Kligfield P. Rhythm annotation and interobserver          reproducibility of measures of heart rate variability. American Journal of Cardiology 1996;78:1055-1057.

 

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