The Institute's research focuses on defining the biology of regurgitant valvular diseases. Our work investigates how heart valve function interacts with the patient, the heart muscle, and the cells and genes of the heart.
Institute research centers on identifying the best heart valve treatments and the most advantageous time to administer them.
Currently, the primary treatment for patients with valve disease is surgery. We are continually working to improve surgical methods, while devoting our energies to perfecting knowledge about the optimum time to perform surgery.
The decision to operate is based on a judgment about what is likely to happen over time — if the operation is performed — versus what is likely to happen if the operation is withheld. These judgments are called prognoses.
Institute-developed Evaluation Tools
Accurate prognoses are based on research that relates the condition of the heart, at initial evaluation, to what will happen later. These studies require accurate and precise measuring tools.
Our team has developed these tools — now being used around the world. Currently, Institute researchers are studying non-invasive imaging methods with and without radioisotopes to further refine these measurements and their optimal interpretation.